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关于此项目
经验公式(希尔记法):
C43H78N5O11P
化学文摘社编号:
分子量:
872.08
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
16:0 NBD PE, Avanti Research™ - A Croda Brand 810144C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810144C-1mg), pkg of 5 × 1 mL (810144C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810144C
concentration
1 mg/mL (810144C-1mg), 1 mg/mL (810144C-5mg)
shipped in
dry ice
storage temp.
−20°C
Application
16:0 NBD PE is suitable:
- for use in the bilayer, as fluorescent probe, together with encapsulated doxorubicin (DXR) for the preparation of planar-supported lipid bilayers (PSLB) of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)
- used in fluorescence control experiment
- for labelling giant plasma membrane vesicles
Biochem/physiol Actions
L-α-Phosphatidylethanolamine maintains membrane integrity.
General description
16:0 NBD PE is a headgroup labelled fluorescent phospholipid. Phosphatidylethanolamine (PE) is the most abundant phospholipid in bacteria and the second most abundant in animals, plants and yeast.
Packaging
5 mL Amber Glass Screw Cap Vial (810144C-1mg)
5 mL Amber Glass Screw Cap Vial (810144C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品(2类)
此项目有
Federico Mazur et al.
Langmuir : the ACS journal of surfaces and colloids (2020-02-26)
Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles
1, 2-diacyl-phosphatidylcholine flip-flop measured directly by sum-frequency vibrational spectroscopy
Liu J and Conboy JC
Biophysical Journal, 89(4), 2522-2532 (2005)
Mesha Saeed et al.
International journal of nanomedicine, 14, 2069-2089 (2019-04-17)
Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using
Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles
Sengupta P, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(1), 20-32 (2008)
Sindy Müller et al.
Pharmaceutics, 11(12) (2019-12-11)
The use of archaeal lipids and their artificial analogues, also known as bolalipids, represents a promising approach for the stabilization of classical lipid vesicles for oral application. In a previous study, we investigated the mixing behavior of three single-chain alkyl-branched
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