810184P
Avanti
TopFluor™ PI(4,5)P2
Avanti Research™ - A Croda Brand
别名:
1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (ammonium salt)
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所有图片(2)
About This Item
经验公式（希尔记法）:
C50H78BF2N3O20P3
CAS Number:
分子量:
1182.89
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
Product Name
TopFluor™ PI(4,5)P2, Avanti Research™ - A Croda Brand 810184P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 50 μg (with stopper and crimp cap (810184P-50ug))
制造商/商品名称
Avanti Research™ - A Croda Brand 810184P
运输
dry ice
储存温度
−20°C
一般描述
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
应用
TopFluor™ PI(4,5)P2 or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI) and in the preparation of giant unilamellar vesicles (GUVs) for the ezrin-membrane tethering assays.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (810184P-50ug)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
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