登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C50H92BF2N6O20P3
化学文摘社编号:
分子量:
1239.02
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
TopFluor™ PI(3,5)P2, Avanti Research™ - A Croda Brand 810186P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (with stopper and crimp cap (810186P-50ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810186P
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Phosphatidylinositol phosphate lipids are associated with serval cell signalling pathways. It participates in the transport of peripheral membrane proteins along the plasma membrane. PI(3,5)P2 is essential for endosome maturation.
General description
PI(3,5)P2 (1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-3,5-bisphosphate) is an endosomal lipid. It is produced by Fab1 phosphatidylinositol-3-phosphate 5-kinase from phosphatidylinositol 3-phosphate. This synthesis occurs in the lysosomal membranes.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810186P-50ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection
Nelson EA, et al.
PLoS Neglected Tropical Diseases, 11(4), e0005540-e0005540 (2017)
The phosphatidylinositol 3, 5-bisphosphate (PI (3, 5) P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis
Han BK and Emr SD
The Journal of Biological Chemistry, 288(28), 20633-20645 (2013)
Interactions and Translational Dynamics of Phosphatidylinositol Bisphosphate (PIP2) Lipids in Asymmetric Lipid Bilayers.
Shi X, et al.
Testing, 32(41), 1732-1741 (2016)
Xiaojun Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 32(7), 1732-1741 (2016-02-02)
Phosphatidylinositol phosphate (PIP) lipids are critical to many cell signaling pathways, in part by acting as molecular beacons that recruit peripheral membrane proteins to specific locations within the plasma membrane. Understanding the biophysics of PIP-protein interactions is critical to developing
Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持