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关于此项目
经验公式（希尔记法）:
C36H61N6O13P
化学文摘社编号:
分子量:
816.88
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810194P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylserine (PS) is an acidic phospholipid enriched in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues. NBD PS is a fluorescently labeled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
Application
18:1-06:0 NBD PS or 1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used as a marker to determine the aminophospholipid transferase activity and in large unilammelar vesicles (LUVs) to investigate the role of phosphatidylinositol 4,5-bisphosphate (PIP2).
Biochem/physiol Actions
Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It supports neuronal survival, neurite growth and synaptogenesis. It is associated with cognitive disability in Alzheimer′s disease.
Packaging
5 mL Amber Glass Screw Cap Vial (810194P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids null
Metabolism and functions of phosphatidylserine
Vance JE and Steenbergen R
Progress in Lipid Research null
R A Zager et al.
Kidney international, 55(1), 148-159 (1999-01-20)
Fluorinated anesthetics can profoundly alter plasma membrane structure and function, potentially impacting cell injury responses. Because major surgery often precipitates acute renal failure, this study assessed whether the most commonly used fluorinated anesthetic, isoflurane, alters tubular cell responses to toxic
The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
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