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Merck
CN

810194P

Avanti

18:1-06:0 NBD PS

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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关于此项目

经验公式(希尔记法):
C36H61N6O13P
化学文摘社编号:
分子量:
816.88
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

18:1-06:0 NBD PS, Avanti Research - A Croda Brand

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810194P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

Application

18:1-06:0 NBD PS or 1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used as a marker to determine the aminophospholipid transferase activity and in large unilammelar vesicles (LUVs) to investigate the role of phosphatidylinositol 4,5-bisphosphate (PIP2).

Biochem/physiol Actions

Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It supports neuronal survival, neurite growth and synaptogenesis. It is associated with cognitive disability in Alzheimer′s disease.

General description

Phosphatidylserine (PS) is an acidic phospholipid enriched in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues. NBD PS is a fluorescently labeled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.

Packaging

5 mL Amber Glass Screw Cap Vial (810194P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Metabolism and functions of phosphatidylserine
Vance JE and Steenbergen R
Progress in Lipid Research null
The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
Isoflurane alters proximal tubular cell susceptibility to toxic and hypoxic forms of attack
Zager RA, et al.
Kidney international reports null
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research null
Involvement of phosphatidylinositol 4, 5-bisphosphate in phosphatidylserine exposure in platelets: use of a permeant phosphoinositide-binding peptide
Bucki R, et al.
Biochemistry null

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