Product Name
C12-NBD Sphingomyelin, Avanti Research™ - A Croda Brand 810219P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810219P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810219P
运输
dry ice
储存温度
−20°C
SMILES字符串
[P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C
InChI
1S/C41H73N6O9P/c1-5-6-7-8-9-10-11-12-13-15-18-21-24-27-38(48)36(34-55-57(52,53)54-33-32-47(2,3)4)43-39(49)28-25-22-19-16-14-17-20-23-26-31-42-35-29-30-37(46(50)51)41-40(35)44-56-45-41/h24,27,29-30,36,38,48H,5-23,25-26,28,31-34H2,1-4H3,(H2-,42,43,45,49,52,
InChI key
FCQMKLRMKNYONQ-YPGNEAGUSA-N
一般描述
C12-NBD Sphingomyelin is a fluorescent analog of biologically active molecule, sphingomyelin. Sphingomyelin is predominantly found in the animal plasma membrane. It is abundantly present as component of cell membranes in mammals, nematodes, protozoa.
应用
C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene.
生化/生理作用
Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SM′s high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membranes, which perform important functions in signal transduction and membrane trafficking.
包装
5 mL Amber Glass Screw Cap Vial (810219P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
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