Merck
CN

810225P

Avanti

18:1 Dansyl PS

Avanti Polar Lipids

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别名:
1,2-dioleoyl-sn-glycero-3-phospho-L-serine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt)
经验公式(希尔记法):
C54H95N4O12PS
分子量:
1055.39
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 1 mg (810225P-1mg)
pkg of 5 × 1 mg (810225P-5mg)

manufacturer/tradename

Avanti Polar Lipids

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidylserine (PS) belongs to the class of glycerophospholipids and is generally found in the inner leaflet of the plasma membrane and in endocytic membranes. Dansyl ((dimethyl amino)naphthalene-1-sulfonYL)) group produces blue or blue-green fluorescent adduct and is used in labeling techniques for studying protein folding and dynamics.(5)

应用

18:1 Dansyl PS may be used for preparation of liposomes for sedimentation assays, visualising and other fluorometric analysis like FRET.

生化/生理作用

Phosphatidylserine (PS) plays a vital role in cell cycle signaling and engulfing apoptotic cells. It is also known to activate the blood coagulation process acting as a pro-coagulant surface.

包装

5 mL Amber Glass Screw Cap Vial (810225P-1mg)
5 mL Amber Glass Screw Cap Vial (810225P-5mg)

储存分类代码

11 - Combustible Solids


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Supplemental Data ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes
Advances in Planar Lipid Bilayers and Liposomes, 125(1), 99-111 (2011)
Laurent Meertens et al.
Cell host & microbe, 12(4), 544-557 (2012-10-23)
Dengue viruses (DVs) are responsible for the most medically relevant arboviral diseases. However, the molecular interactions mediating DV entry are poorly understood. We determined that TIM and TAM proteins, two receptor families that mediate the phosphatidylserine (PtdSer)-dependent phagocytic removal of
Barry R Lentz
Progress in lipid research, 42(5), 423-438 (2003-06-20)
This article addresses the role of platelet membrane phosphatidylserine (PS) in regulating the production of thrombin, the central regulatory molecule of blood coagulation. PS is normally located on the cytoplasmic face of the resting platelet membrane but appears on the
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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