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Merck
CN

810250C

Avanti

25-NBD 胆固醇

Avanti Research - A Croda Brand

别名:

25-[N-[(7-硝基-2-1,3-苯并恶二唑-4-基)甲基]氨基]-27-降胆甾醇

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关于此项目

经验公式(希尔记法):
C33H48N4O4
化学文摘社编号:
分子量:
564.76
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

25-NBD 胆固醇, Avanti Research - A Croda Brand 810250C

SMILES string

[N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCC[C@H]([C@H]3[C@@]4([C@H]([C@H]5[C@@H]([C@]6(CC[C@@H](CC6=CC5)O)C)CC4)CC3)C)C)C)C

InChI

1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1

InChI key

RMGLSQAGXRZCPZ-OVHOIDCTSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810250C-10mg)
pkg of 1 × 1 mL (810250C-1mg)
pkg of 1 × 1 mL (810250C-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810250C

concentration

1 mg/mL (810250C-1mg)
10 mg/mL (810250C-10mg)
5 mg/mL (810250C-5mg)

shipped in

dry ice

storage temp.

−20°C

Application

25-NBD胆固醇可用作共聚焦显微镜的标记物,用于研究内体运输和囊泡形成。

Biochem/physiol Actions

胆固醇通过一系列酶促反应(称为甲羟戊酸途径)合成。胆固醇在质膜的结构和稳定性中起主要作用,并且还参与胆钙化醇(维生素D3)的合成。胆固醇在血管壁或动脉上聚积会导致血流阻塞,导致严重疾病动脉硬化。它是胆汁酸和类固醇激素(如孕酮、睾酮、皮质醇和醛固酮)合成的前体。

General description

25-NBD胆固醇是胆固醇的荧光衍生物。其荧光特性是由于存在NBD(2-(4-硝基-2,1,3-苯并恶二唑-7-基)氨乙基)基团。

Packaging

5 mL透明玻璃密封安瓿 (810250C-10mg)
5 mL透明玻璃密封安瓿 (810250C-1mg)
5 mL透明玻璃密封安瓿 (810250C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品(2类)
此项目有

历史批次信息供参考:

分析证书(COA)

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