810263P
Avanti
C11 TopFluor™ Dihydroceramide
Avanti Research™ - A Croda Brand
别名:
N-[11-(TopFluor)undecanoyl]-D-erythro-sphinganine
产品名称
C11 TopFluor™ Dihydroceramide, N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphinganine, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 250 μg (810263P-250ug)
制造商/商品名称
Avanti Research™ - A Croda Brand 810263P
运输
dry ice
储存温度
−20°C
一般描述
There are two types of dihydroceramide desaturases, such as DES1 and DES2. DES1 is ubiquitously present and DES2 is present in the gut and skin.
生化/生理作用
Dihydroceramide (DH-Cer) plays a key role in de novo biosynthesis of sphingolipid by acting as an intermediate. Dihydroceramide modulates autophagy. This metabolite can stimulate fibrosis in hepatic steatosis model. It can enhance the lipid droplets by damaging the autophagic flux.
包装
5 mL Amber Glass Screw Cap Vial (810263P-250ug)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
法规信息
新产品
此项目有
Dihydroceramide Biology STRUCTURE-SPECIFIC METABOLISM AND INTRACELLULAR LOCALIZATION
Kok JW, et al.
The Journal of Biological Chemistry, 272(34), 21128-21136 (1997)
Dihydroceramides: from bit players to lead actors
Siddique M M, et al.
Test, 290(25), 15371-15379 (2015)
Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model
Lee Ah young, et al.
Biochemical and biophysical research communications, 494(3-4), 460-469 (2017)
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