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关于此项目
经验公式（希尔记法）:
C62H94N3O14P
化学文摘社编号:
分子量:
1136.40
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1 PE CF, Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
solution
packaging
pkg of 1 × 1 mL (810332C-1mg)
pkg of 5 × 1 mL (810332C-5mg)
pkg of 5 × 2 mL (810332C-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (810332C-10mg)
1 mg/mL (810332C-1mg)
1 mg/mL (810332C-5mg)
lipid type
fluorescent lipids
shipped in
dry ice
storage temp.
−20°C
Application
18:1 PE CF may be used:
- to spike human serum
- to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
- to prepare the large unilamellar vesicles (LUVs)
- in the preparation of fluorescent phosphoinositide?containing liposomes
- for fluorescent labeling of total lipids to the initial liposome formulation mixture
- in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding
Biochem/physiol Actions
Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).
General description
Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 PE CF is a green fluorescent tagged phosphatidylethanolamine.
Packaging
5 mL Amber Glass Screw Cap Vial (810332C-10mg)
5 mL Amber Glass Screw Cap Vial (810332C-1mg)
5 mL Amber Glass Screw Cap Vial (810332C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
此项目有
NUTS and BOLTS: applications of fluorescence-detected sedimentation
Kroe RR and Laue TM
Analytical biochemistry, 390(1), 1-13 (2009)
Protein-Lipid Interaction by Fluorescence (PLIF) to Characterize and Screen for Inhibitors of Protein-Phosphoinositide Interactions
Ceccato L, et al.
Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.], 89(1), 19-31 (2017)
Enhanced blood-brain barrier transmigration using a novel transferrin embedded fluorescent magneto-liposome nanoformulation
Ding H, et al.
Nanotechnology, 25(5), 055101-055101 (2014)
Liposome Flotation Assays for Phosphoinositide-protein Interaction
Tronchere H and Boal F
Journal of Cell Science, 390(1), 1-13 (2015)
Yashi Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 321, 71-83 (2020-02-09)
Oxidative-stress defense system stands for the vulnerability of tumor cells because of the stronger oxidative stress existing in tumor sites. TRPA-1 has been found to be overexpressed in various tumors, related to the tumor proliferation and metastasis, and promote reactive
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