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Merck
CN

810600C

Avanti

16:0-12 Doxyl PC

Avanti Research - A Croda Brand

别名:

1-palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C46H90N2O10P
化学文摘社编号:
分子量:
862.19
UNSPSC代码:
51321705
NACRES:
NA.25
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产品名称

16:0-12 Doxyl PC, Avanti Research - A Croda Brand 810600C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (810600C-1mg)

制造商/商品名称

Avanti Research - A Croda Brand 810600C

浓度

1 mg/mL (810600C-1mg)

脂质类型

phospholipids
ESR probes

运输

dry ice

储存温度

−20°C

一般描述

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

包装

5 mL Clear Glass Sealed Ampule (810600C-1mg)

制备说明

To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM.,Supplemental information

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kervin O Evans et al.
Biochimica et biophysica acta, 1848(5), 1175-1182 (2015-02-18)
The phenols hydroxytyrosol and tyrosol made abundantly available through olive oil processing were enzymatically transesterified into effective lipophilic antioxidants with cuphea oil. The hydroxytyrosyl and tyrosyl esters made from cuphea oil were assessed for their ability to partition into, locate
Ling Yan et al.
FEBS letters, 555(3), 545-550 (2003-12-17)
We investigated the ability of tBid (truncated form of Bid) to bind and permeabilize the liposomes (large unilamellar vesicles, LUVs) and release fluorescent marker molecules (fluorescein-isothiocyanate-conjugated dextrans, FITC-dextrans) of various molecular diameters (FD-20, FD-70, FD-250S) from LUVs. Obtained data showed
L A Falls et al.
The Journal of biological chemistry, 276(26), 23895-23902 (2001-04-20)
The hydrophobic omega-loop within the prothrombin gamma-carboxyglutamic acid-rich (Gla) domain is important in membrane binding. The role of this region in membrane binding was investigated using a synthetic peptide, PT-(1-46)F4W, which includes the N-terminal 46 residues of human prothrombin with
Bhagyashree D Rao et al.
Chemistry and physics of lipids, 226, 104849-104849 (2019-12-15)
pH (low) insertion peptide (pHLIP) is a polypeptide from the third transmembrane helix of bacteriorhodopsin. The pH-dependent membrane insertion of pHLIP has been conveniently exploited for translocation of cargo molecules and as a novel imaging agent in cancer biology due
Local polarity and hydrogen bonding inside the Sec14p phospholipid-binding cavity: high-field multi-frequency electron paramagnetic resonance studies.
Smirnova TI, et al.
Biophysical Journal, 92, 3686-3695 (2007)

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