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Merck
CN

830841C

Avanti

06:0 PA

Avanti Research™ - A Croda Brand

别名:

1,2-dicaproyl-sn-glycero-3-phosphate (sodium salt); PA(6:0/6:0)

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关于此项目

经验公式（希尔记法）:
C15H28O8PNa
化学文摘社编号:
321883-53-8
分子量:
390.34
UNSPSC代码:
12352211
NACRES:
NA.25

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产品名称

06:0 PA, 1,2-dihexanoyl-sn-glycero-3-phosphate (sodium salt), chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (830841C-10mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 830841C

浓度

10 mg/mL (830841C-10mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O)=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]

InChI

1S/C15H29O8P.Na/c1-3-5-7-9-14(16)21-11-13(12-22-24(18,19)20)23-15(17)10-8-6-4-2;/h13H,3-12H2,1-2H3,(H2,18,19,20);/q;+1/p-1/t13-;/m1./s1

InChI key

RSKVQVAHZSAALH-BTQNPOSSSA-M

一般描述

Phosphatidic acid synthesis from phosphatidylcholine is mediated by phospholipase D.

应用

06:0 PA may be used in liposome flotation assay to study its interactions between purified dynamin-related protein 1 (Drp1). It may also be used to study its effect in coat protein I (COPI) vesicle fission and transport. It has been used in the preparation of the ubiquitin specific peptidase 1- mitochondrial distribution and morphology protein 35 (Ups1–Mdm35)– phosphatidic acid (PA) complex for crystallization studies.

生化/生理作用

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid.

包装

5 mL Clear Glass Sealed Ampule (830841C-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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分析证书(COA)

Lot/Batch Number

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Glycerolipids in signal transduction
New comprehensive biochemistry, 31, 237-255 (1996)
Yoshihiro Adachi et al.
Bio-protocol, 7(9) (2017-08-25)
A mitochondrion is a dynamic intracellular organelle that actively divides and fuses to control its size, number and shape in cells. A regulated balance between mitochondrial division and fusion is fundamental to the function, distribution and turnover of mitochondria (Roy
Seung-Yeol Park et al.
Nature communications, 10(1), 3409-3409 (2019-08-01)
Studies on vesicle formation by the Coat Protein I (COPI) complex have contributed to a basic understanding of how vesicular transport is initiated. Phosphatidic acid (PA) and diacylglycerol (DAG) have been found previously to be required for the fission stage
Yasunori Watanabe et al.
Nature communications, 6, 7922-7922 (2015-08-04)
Eukaryotic cells are compartmentalized into membrane-bounded organelles whose functions rely on lipid trafficking to achieve membrane-specific compositions of lipids. Here we focused on the Ups1-Mdm35 system, which mediates phosphatidic acid (PA) transfer between the outer and inner mitochondrial membranes, and

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