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关于此项目
经验公式(希尔记法):
C31H60O8PNa
化学文摘社编号:
分子量:
614.77
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
14:0 PA, Avanti Research™ - A Croda Brand
form
powder
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)O
InChI
1S/C31H61O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(32)37-27-29(28-38-40(34,35)36)39-31(33)26-24-22-20-18-16-14-12-10-8-6-4-2;/h29H,3-28H2,1-2H3,(H2,34,35,36);/q;+1/p-1/t29-;/m1./s1
InChI key
UBSPGYHFNIKQIP-XXIQNXCHSA-M
description
1,2-dimyristoyl-sn-glycero-3-phosphate (sodium salt)
assay
>99% (TLC)
packaging
pkg of 1 × 200 mg (830845P-200mg)
pkg of 1 × 25 mg (830845P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
14:0 PA可用于制备脂质体。它也可以用作磷脂(PL)标准品,以定量磷脂酸(PA)。
Biochem/physiol Actions
磷脂酸可用作吞噬细胞呼吸爆发的调节剂。它也是二酰基甘油和溶血磷脂酸的前体。
General description
磷脂酸是在磷脂酶D的帮助下从甘油磷脂获得的。14:0 PA/a带负电荷的1,2-二肉豆蔻酰基-sn-甘油-3-磷酸酯(DMPA)带有磷酸头基。
Packaging
5 mL棕色玻璃螺旋盖小瓶(830845P-200mg)
5 mL棕色玻璃螺旋盖小瓶(830845P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Wenjie Wang et al.
The journal of physical chemistry. B, 116(24), 7213-7220 (2012-05-23)
Although a minor component of the lipidome, phosphatidic acid (PA) plays a crucial role in nearly all signaling pathways involving cell membranes, in part because of its variable electrical charge in response to environmental conditions. To investigate how charge is
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Xu Q, et al.
Biomaterials, 28(16), 2687-2694 (2007)
Chiaki Murakami et al.
The Journal of biological chemistry, 295(10), 2932-2947 (2020-01-26)
The δ isozyme of diacylglycerol kinase (DGKδ) plays critical roles in lipid signaling by converting diacylglycerol (DG) to phosphatidic acid (PA). We previously demonstrated that DGKδ preferably phosphorylates palmitic acid (16:0)- and/or palmitoleic acid (16:1)-containing DG molecular species, but not
Glycerolipids in signal transduction
Lambeth JD and Ryu SH
New comprehensive biochemistry, 31, 237-255 (1996)
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