产品名称
PAF (from Heart PC), Avanti Research™ - A Croda Brand 840009C
InChI
1S/C12H26NO7P/c1-6-17-9-12(20-11(2)14)10-19-21(15,16)18-8-7-13(3,4)5/h12H,6-10H2,1-5H3/t12-/m1/s1
InChI key
OLGKYSVSAKLUHK-GFCCVEGCSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (840009C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840009C
concentration
5 mg/mL (840009C-5mg)
lipid type
lipid extracts
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
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General description
Platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), an endogenous phospholipid is synthesized by several cells. PAF is a phosphatidylcholine derivative.
Biochem/physiol Actions
Platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is linked with arterial thrombosis, endotoxic shock, acute inflammation and acute allergic disease. It acts as a mediator of pathogenesis of ulcerative colitis and Crohn′s disease in human colon. It also participates in platelet activation and inflammation.
Packaging
5 mL Clear Glass Sealed Ampule (840009C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
PAFAH Ib phospholipase A2 subunits have distinct roles in maintaining Golgi structure and function
Bechler ME and Brown WJ
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831(3), 595-601 (2013)
Thromboxane A2-mediated Cl- secretion induced by platelet-activating factor in isolated rat colon
Suzuki T, et al.
European Journal of Pharmacology, 400(2-3), 297-303 (2000)
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