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Merck
CN

840029P

Avanti

18:0 PS

Avanti Research™ - A Croda Brand

别名:

1,2-双十八烷酰基-sn-甘油-3-磷酸-L-丝氨酸（钠盐）；DSPS；PS(18:0/18:0)；110671

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关于此项目

经验公式（希尔记法）:
C42H81NO10PNa
CAS Number:
321595-13-5
分子量:
814.06
MDL编号:
MFCD00145110
UNSPSC代码:
12352211
NACRES:
NA.25

主要文件

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描述

1,2-distearoyl-sn-glycero-3-phospho-L-serine (sodium salt)

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 10 mg (840029P-10mg)
pkg of 1 × 25 mg (840029P-25mg)
pkg of 1 × 500 mg (840029P-500mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

相关类别

一般描述

磷脂酰丝氨酸（PS）是一种氨基磷脂，带负电荷，占细胞总脂质的2-10%。它位于膜小叶中。

应用

18:0 PS已用于通过表面等离子体共振（SPR）技术评估其对细胞色素c的亲和力，并用于制备磷脂囊泡。可用于制备聚二甲基硅氧烷（PDMS）杂化微泡。

生化/生理作用

磷脂酰丝氨酸（PS）在蛋白激酶C途径中起关键作用。它还有助于将细胞内蛋白质限制在细胞质的膜小叶中。

包装

20 mL透明玻璃螺旋盖小瓶（840029P-500mg）
5 mL棕色玻璃螺旋盖小瓶（840029P-10mg）
5 mL棕色玻璃螺旋盖小瓶（840029P-25mg）

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kanaka Hettiarachchi et al.
Journal of colloid and interface science, 344(2), 521-527 (2010-02-19)
Polymer-lipid microbubbles (PLBs) are generated by microfluidic flow-focusing devices to form a new class of long-lasting hybrid particles. The specific PLB construct developed is an elastic gas-filled microsphere with a polydimethylsiloxane (PDMS) shell containing phospholipids conjugated to functionalized polyethyleneglycol (PEG).
Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
German Stepanov et al.
FEBS letters, 583(1), 97-100 (2008-12-09)
We attempted to evaluate the affinity of the anionic phospholipids to cytochrome c by means of surface plasmon resonance (SPR) technique and to correlate it with the cytochrome c active site alterations and peroxidase activity. Our experiments showed a strong
Pooja Jha et al.
Cell systems, 6(6), 709-721 (2018-06-18)
The genetic regulation and physiological impact of most lipid species are unexplored. Here, we profiled 129 plasma lipid species across 49 strains of the BXD mouse genetic reference population fed either chow or a high-fat diet. By integrating these data with genomics
Jung Yong Eum et al.
Journal of chromatography. A, 460849-460849 (2020-01-14)
Aging refers to the intracellular accumulation of reactive oxygen species that damages proteins, DNA, and lipids. As alterations in lipid metabolism may trigger metabolic disorders and the onset of metabolic diseases, changes in lipid profiles can be closely related to
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