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Merck
CN

840066C

Avanti

20:4 PS

Avanti Research™ - A Croda Brand

别名:

1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DAPS; PS(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))

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关于此项目

经验公式（希尔记法）:
C46H73NO10PNa
化学文摘社编号:
474967-17-4
分子量:
854.04
UNSPSC代码:
12352211
NACRES:
NA.25

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产品名称

20:4 PS, 1,2-diarachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (840066C-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 840066C

浓度

10 mg/mL (840066C-25mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[Na+]

InChI

1S/C46H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-44(48)54-39-42(40-55-58(52,53)56-41-43(47)46(50)51)57-45(49)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h11-14,17-20,23-26,29-32,42-43H,3-10,15-16,21-22,27-28,33-41,47H2,1-2H3,(H,50,51)(H,52,53);/q;+1/p-1/b13-11-,14-12-,19-17-,20-18-,25-23-,26-24-,31-29-,32-30-;/t42-,43+;/m1./s1

InChI key

JFPYEVXNLNLLRD-LAECUUORSA-M

一般描述

20:4 PS or 1,2-diarachidonoyl-sn-glycero-3-phospho-L-serine is a sodium salt of glycerophospholipid having two chains of arachidonic acid attached to the sn-1 and sn-2 positions and phospho-L-serine at the sn-3 position of the glycerol backbone.

应用

20:4 PS or 1,2-diarachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt) has been used in liposome preparation to study effects of the fatty acid (FA) profile of phospholipids on membrane vesiculation by dynamin and endophilin.

包装

5 mL Clear Glass Sealed Ampule (840066C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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