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Merck
CN

840419P

Avanti

16:0 Phosphatidylmethanol

Avanti Research™ - A Croda Brand

别名:

1,2-dihexadecanoyl-sn-glycero-3-phosphomethanol (sodium salt)

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关于此项目

经验公式（希尔记法）:
C36H70O8PNa
化学文摘社编号:
92609-89-7
分子量:
684.90
MDL number:
MFCD22495315
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

16:0 Phosphatidylmethanol, 1,2-dipalmitoyl-sn-glycero-3-phosphomethanol (sodium salt), powder

SMILES string

[H][C@@](COP([O-])(OC)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C36H71O8P.Na/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-35(37)42-32-34(33-43-45(39,40)41-3)44-36(38)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h34H,4-33H2,1-3H3,(H,39,40);/q;+1/p-1/t34-;/m1./s1

InChI key

JDEIVNUSWULHEB-MDYNBEAQSA-M

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840419P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840419P

shipped in

dry ice

storage temp.

−20°C

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Application

16:0 Phosphatidylmethanol (1,2-dipalmitoyl-sn-glycero-3-phosphomethanol (sodium salt)) may be used as a standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) analysis for the quantification of phosphatidylethanols (PEths) in whole blood, venous/capillary-dried blood spots (V-DBS and C-DBS).

Biochem/physiol Actions

Phosphatidylmethanol is an anionic lipid which binds to the Phospholipase D. It is categorized as an alkyl phosphate lipid under headgroup modified lipids.

Packaging

5 mL Amber Glass Screw Cap Vial (840419P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

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K Stieglitz et al.
The Journal of biological chemistry, 274(50), 35367-35374 (1999-12-10)
The Streptomyces chromofuscus phospholipase D (PLD) cleavage of phosphatidylcholine in bilayers can be enhanced by the addition of the product phosphatidic acid (PA). Other anionic lipids such as phosphatidylinositol, oleic acid, or phosphatidylmethanol do not activate this PLD. This allosteric
Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and

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