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关于此项目
经验公式(希尔记法):
C37H68O8PNa
化学文摘社编号:
分子量:
694.89
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
16:0-18:2 PA, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 mg (840858P-100mg), pkg of 1 × 25 mg (840858P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840858P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C37H69O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35H,3-10,12,14-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b13-11-,18-17-;/t35-;/m1./s1
InChI key
IYNPOFCKGPJAFU-HQFKUYMNSA-M
General description
磷脂酸(PA)是一种阴离子膜结构脂质。它本质上是两亲性的,包含一个极性头基和两个长的疏水性酰基链。PA充当更复杂的膜磷脂的母体化合物。16:0-18:2 PA或1-棕榈酰基-2-亚油酰基-sn-甘油-3-磷酸是磷脂酸的钠盐,在甘油主链中在sn-1和sn-2的位置处分别被棕榈酸和亚麻酸取代。
Application
16:0-18:2 PA或1-棕榈酰基-2-亚油酰基-sn-甘油-3-磷酸酯(钠盐)可用作薄层色谱(TLC)的标准品,用于分离生姜和葡萄柚外来体样纳米颗粒(ELN)衍生的脂质。它也可用于滤膜印迹分析,以研究含有AT钩基序的核定位蛋白4(Ahl4)与PA的交互效应。
Biochem/physiol Actions
磷脂酸(PA)是一种生物活性脂质,可作为次级信使。它与中性粒细胞中过氧化氢的产生有关。PA刺激蛋白激酶对中性粒细胞呼吸爆发的作用。它也参与Ras介导的信号通路。PA与水和其他磷脂反应分别产生脂质双层和多组分双层。
Packaging
5 mL透明玻璃密封安瓿(840858P-100mg)
5 mL透明玻璃密封安瓿(840858P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Bioactive Lipids
An Introduction to Biological Membranes, ,
number=(,
pages=), 453-478 (2016)
Guangqin Cai et al.
Molecular plant, 13(7), 984-1000 (2020-04-26)
Lipid catabolism in germinating seeds provides energy and substrates for initial seedling growth, but how this process is regulated is not well understood. Here, we show that an AT-hook motif-containing nuclear localized (AHL) protein regulates lipid mobilization and fatty acid
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 840858P-25MG | 04061835226955 |