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Merck
CN

840886C

Avanti

20:4 PA

Avanti Research™ - A Croda Brand

别名:

1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate (sodium salt); DAPA; PA(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))

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关于此项目

经验公式（希尔记法）:
C43H68O8PNa
化学文摘社编号:
474943-33-4
分子量:
766.96
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

20:4 PA, 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt), chloroform

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[Na+]

InChI

1S/C43H69O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-42(44)49-39-41(40-50-52(46,47)48)51-43(45)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h11-14,17-20,23-26,29-32,41H,3-10,15-16,21-22,27-28,33-40H2,1-2H3,(H2,46,47,48);/q;+1/p-1/b13-11-,14-12-,19-17-,20-18-,25-23-,26-24-,31-29-,32-30-;/t41-;/m1./s1

InChI key

FDDKKAHLSUVCLC-QHEFBXHFSA-M

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840886C-25mg)
pkg of 2 × 4 mL (840886C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840886C

concentration

10 mg/mL (840886C-25mg)
25 mg/mL (840886C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) has been used as a supplement in mouse chow to see changes in small intestine gene expression.

General description

Phosphatidic acid (PA) is a precursor of lysophosphatidic acid (LPA) and is present in leafy vegetables. 20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) is a sodium salt of phosphatidic acid, with substitution of two chains of arachidonic acid at the sn-1 and sn-2 positions, in the glycerol backbone.

Packaging

5 mL Clear Glass Sealed Ampule (840886C-200mg)
5 mL Clear Glass Sealed Ampule (840886C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mohamad Navab et al.
Journal of lipid research, 54(12), 3403-3418 (2013-10-03)
We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR⁻/⁻) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but

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