产品名称
04:0 PC, 1,2-dibutyryl-sn-glycero-3-phosphocholine, chloroform
InChI
1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1
InChI key
QIJYAMAPPUXBSC-CQSZACIVSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850303C-25mg), pkg of 1 × 20 mL (850303C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850303C
concentration
10 mg/mL (850303C-25mg), 25 mg/mL (850303C-500mg)
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylcholine (PC) is dietary source of choline. 04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) is a short chain fatty acyl residue.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) may be used:
- to study its influence on the formation of lipid hydroperoxides and headspace hexanal in stripped soybean oil (SSO)
- to study its impact on the antioxidant activity of α-tocopherol
- as a phospholipid substrate to study the substrate specificity of the purified glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP)
- as a substrate to study the activities of soluble and immobilized phospholipase 2 from snake venom
Biochem/physiol Actions
Phosphatidylcholine (PC) intake through diet can enhance the learning and memory ability in rats.
Packaging
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850303C-500mg)
5 mL Clear Glass Sealed Ampule (850303C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
新产品
此项目有
Z Shen et al.
Journal of lipid research, 36(5), 1147-1151 (1995-05-01)
A new method for the immobilization of phospholipase A2 (PLA2) has been developed to enhance the activity retention of immobilized PLA2. When PLA2 from the venom of Agkistrodon piscivorus piscivorus was pretreated with 4-nitro-3-octanoyl-oxybenzoic acid to acylate epsilon-amino groups of
Bingcan Chen et al.
Food & function, 2(6), 302-309 (2011-07-23)
Phospholipids self-assemble in bulk oils to form structures such as reverse micelles that can alter the microenvironment where chemical degradation reactions occur, such as lipid oxidation. In this study, we examined the influence of phospholipid reverse micelles on the activity
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
T Bukowski et al.
Biochemistry, 25(24), 8024-8033 (1986-12-02)
The dimerization of phospholipase A2 (PLPA2) from Naja naja naja (Pakistani cobra) and Crotalus atrox (Western Diamondback rattlesnake) has been studied from pH 2.5 to 11 at 20 degrees C in 1 mM CaCl2, 0.21 M ionic strength. For the
L Cornacchia et al.
Biochemical and biophysical research communications, 231(2), 277-282 (1997-02-13)
Phosphatidylcholines (PC) are secreted into the bile via a membrane transport protein(s). Recently, evidence for ATP-dependent mdr2-encoded PC transport as well as for carrier-mediated PC transport had been reported. Therefore, we investigated whether mdr2 P-glycoprotein is involved in the transport
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