产品名称
04:0 PC, 1,2-dibutyryl-sn-glycero-3-phosphocholine, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COC(CCC)=O)=O
InChI
1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1
InChI key
QIJYAMAPPUXBSC-CQSZACIVSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850303P-25mg), pkg of 1 × 500 mg (850303P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850303P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
04:0 PC is a water soluble phophatidylcholine analogue. Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
04:0 PC is suitable for use to evaluate its ability to form reverse micelles. It is also suitable for use as a phospholipid substrate to study the substrate specificity of glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP).
Biochem/physiol Actions
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
Packaging
30 mL Amber Wide Mouth Bottle with Screw Cap (850303P-500mg)
5 mL Clear Glass Sealed Ampule (850303P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
The Membranes of Cells (2016)
Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of alpha-tocopherol and Trolox
Chen B, et al.
Food & Function, 2(6), 302-309 (2011)
Integrative Medicine - E-Book (2017)
Characterization of glycerophosphoethanolamine ethanolaminephosphodiesterase from Streptomyces sanglieri
Mineta S, et al.
Journal of Bioscience and Bioengineering, 119(2), 123-130 (2015)
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
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