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Merck
CN

850305C

Avanti

06:0 PC (DHPC)

Avanti Research™ - A Croda Brand

别名:

DHPC; 1,2-dicaproyl-sn-glycero-3-phosphocholine; PC(6:0/6:0)

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关于此项目

经验公式（希尔记法）:
C20H40NO8P
化学文摘社编号:
34506-67-7
分子量:
453.51
MDL number:
MFCD00050431
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

06:0 PC (DHPC), 1,2-dihexanoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(OC(=O)CCCCC)COC(=O)CCCCC

InChI

1S/C20H40NO8P/c1-6-8-10-12-19(22)26-16-18(29-20(23)13-11-9-7-2)17-28-30(24,25)27-15-14-21(3,4)5/h18H,6-17H2,1-5H3

InChI key

DVZARZBAWHITHR-UHFFFAOYSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850305C-25mg)
pkg of 2 × 20 mL (850305C-1g)
pkg of 2 × 4 mL (850305C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850305C

concentration

10 mg/mL (850305C-25mg)
25 mg/mL (850305C-1g)
25 mg/mL (850305C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

06:0 PC (1,2-dihexanoyl-sn-glycero-3-phosphocholine/DHPC) may be used:
  • in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
  • to form lipid vesicles/micelles for guanosine triphosphate (GTP) hydrolysis (GTPase) assays
  • in the reconstitution of p7 protein of the hepatitis C virus (p7(5a)) in bicelles

Biochem/physiol Actions

Phosphatidylcholines (PCs) plays a functional role in reducing the level of blood lipid and cholesterol. It may also have the ability to inhibit cardiovascular disease and obesity.

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs are known to carry saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850305C-1g)
5 mL Clear Glass Sealed Ampule (850305C-200mg)
5 mL Clear Glass Sealed Ampule (850305C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

易制毒化学品（2类）
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lipid binding by disordered proteins
Perez Y, et al.
Protocol Exchange, 10 null
Mutagenesis and peptide analysis of the DRY motif in the alpha 2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors
Chung DA, et al.
Biochemical and biophysical research communications, 293(4), 1233-1241 null
Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Bhagavan NV, et al.
Essentials of Medical Biochemistry, 299-320 null
Gabriel A Cook et al.
Biochemistry, 52(31), 5295-5303 (2013-07-12)
Hepatitis C virus (HCV) protein p7 plays an important role in the assembly and release of mature virus particles. This small 63-residue membrane protein has been shown to induce channel activity, which may contribute to its functions. p7 is highly
Qinghai Zhang et al.
Journal of the American Chemical Society, 130(23), 7357-7363 (2008-05-16)
The rate limiting step in biophysical characterization of membrane proteins is often the availability of suitable amounts of protein material. It was therefore of interest to demonstrate that microcoil nuclear magnetic resonance (NMR) technology can be used to screen microscale
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