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Merck
CN

850312C

Avanti

DOCPe

Avanti Research - A Croda Brand

别名:

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

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关于此项目

经验公式(希尔记法):
C45H86NO8P
化学文摘社编号:
分子量:
800.14
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

DOCPe, Avanti Research - A Croda Brand 850312C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850312C-25mg), pkg of 2 × 4 mL (850312C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850312C

concentration

10 mg/mL (850312C-25mg), 25 mg/mL (850312C-200mg)

shipped in

dry ice

storage temp.

−20°C

General description

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethylphosphate (DOCPe) is a neutrally charged lipid.
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

Application

DOCPe is suitable for liposomes preparation. It is also suitable to use as membrane to examine the impact of the phospholipid head on peptide-membrane interaction.

Packaging

5 mL Clear Glass Sealed Ampule (850312C-200mg)
5 mL Clear Glass Sealed Ampule (850312C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles
Wang X, et al.
Langmuir (2018)
Partition of Positively and Negatively Charged Tryptophan Ions in Membranes with Inverted Phospholipid Heads: Simulations and Experiments
Cardenas AE, et al.
The Journal of Physical Chemistry B, 123(15), 3272-3281 (2019)
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids



全球贸易项目编号

货号GTIN
850312C-200MG04061837791925