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Merck
CN

850330C

Avanti

11:0 PC

Avanti Research™ - A Croda Brand

别名:

PC(11:0/11:0)

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关于此项目

经验公式（希尔记法）:
C30H60NO8P
化学文摘社编号:
27869-47-2
分子量:
593.77
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

11:0 PC, 1,2-diundecanoyl-sn-glycero-3-phosphocholine, chloroform

lipid type

phospholipids
cardiolipins

InChI

1S/C30H60NO8P/c1-6-8-10-12-14-16-18-20-22-29(32)36-26-28(27-38-40(34,35)37-25-24-31(3,4)5)39-30(33)23-21-19-17-15-13-11-9-7-2/h28H,6-27H2,1-5H3

InChI key

XCCDCYFQYUARAY-UHFFFAOYSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850330C-25mg), pkg of 1 × 20 mL (850330C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850330C

concentration

10 mg/mL (850330C-25mg), 25 mg/mL (850330C-500mg)

shipped in

dry ice

storage temp.

−20°C

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General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
Phosphatidylcholine (PC) is the chief phospholipid present in the mammalian tissues. It accounts to 50% of total phospholipid content of the cell. PC has one head comprising choline and phosphate; two tails of fatty acids. Generally, PC from mammalian tissues contains saturated fatty acid in the C1 position and unsaturated fatty acyl in the C2 position of the glycerol.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

11:0 PC (1,2-diundecanoyl-sn-glycero-3-phospho choline) has been used:
  • to supplement with bacteria to feed L4 larvae for Caenorhabditis elegans fat content measurement
  • in the preparation of liposomes
  • as an internal standard during lipid extraction and subsequent liquid chromatography-mass spectrometry (LC-MS) analysis

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
Phosphatidylcholine (PC) synthesis is stimulated by certain hormones, growth factors and phorbol esters by the action of phosphocholine cytidyltransferase. Hydrolysis of PC plays a key role in cell signaling.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850330C-500mg)
5 mL Clear Glass Sealed Ampule (850330C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品（2类）
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Signaling through phosphatidylcholine breakdown.
Exton JH
The Journal of Biological Chemistry, 265(1), 1-4 (1990)
Skp is a multivalent chaperone of outer-membrane proteins
Schiffrin B, et al.
Nature Structural and Molecular Biology, 23(9), 786-786 (2016)
The regulation and cellular functions of phosphatidylcholine hydrolysis.
Billah MM and Anthes JC
The Biochemical Journal, 269(2), 281-281 (1990)
Effects of periplasmic chaperones and membrane thickness on BamA-catalyzed outer-membrane protein folding
Schiffrin B, et al.
Journal of Molecular Biology, 429(23), 3776-3792 (2017)
Integrative Medicine - E-Book (2017)
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