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Merck
CN

850330C

Avanti

11:0 PC

Avanti Research - A Croda Brand

别名:

PC(11:0/11:0)

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About This Item

经验公式(希尔记法):
C30H60NO8P
CAS Number:
分子量:
593.77
UNSPSC代码:
12352211
NACRES:
NA.25

价格与库存信息目前不能提供

Product Name

11:0 PC, 1,2-diundecanoyl-sn-glycero-3-phosphocholine, chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (850330C-25mg)
pkg of 1 × 20 mL (850330C-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 850330C

浓度

10 mg/mL (850330C-25mg)
25 mg/mL (850330C-500mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

InChI

1S/C30H60NO8P/c1-6-8-10-12-14-16-18-20-22-29(32)36-26-28(27-38-40(34,35)37-25-24-31(3,4)5)39-30(33)23-21-19-17-15-13-11-9-7-2/h28H,6-27H2,1-5H3

一般描述

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[1] It is also an important component of the mucosal layer of the colon.[2]
Phosphatidylcholine (PC) is the chief phospholipid present in the mammalian tissues. It accounts to 50% of total phospholipid content of the cell. PC has one head comprising choline and phosphate; two tails of fatty acids.[3] Generally, PC from mammalian tissues contains saturated fatty acid in the C1 position and unsaturated fatty acyl in the C2 position of the glycerol.[4]
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

11:0 PC (1,2-diundecanoyl-sn-glycero-3-phospho choline) has been used:
  • to supplement with bacteria to feed L4 larvae for Caenorhabditis elegans fat content measurement[5]
  • in the preparation of liposomes[6][7]
  • as an internal standard during lipid extraction and subsequent liquid chromatography-mass spectrometry (LC-MS) analysis[8]

生化/生理作用

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[2] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[9]
Phosphatidylcholine (PC) synthesis is stimulated by certain hormones, growth factors and phorbol esters by the action of phosphocholine cytidyltransferase. Hydrolysis of PC plays a key role in cell signaling.[10]

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850330C-500mg)
5 mL Clear Glass Sealed Ampule (850330C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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