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关于此项目
经验公式（希尔记法）:
C36H68NO8P
化学文摘社编号:
分子量:
673.90
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
产品名称
14:1 (Δ9-Cis) PC, 1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850346C-25mg), pkg of 2 × 4 mL (850346C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850346C
concentration
10 mg/mL (850346C-25mg), 25 mg/mL (850346C-200mg)
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.
Biochem/physiol Actions
Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
Packaging
5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
The Membranes of Cells (2016)
Phosphatidylcholine and cell death
Cui Z and Houweling M
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1585(2-3), 87-96 (2002)
Jiao Cao et al.
Nature communications, 10(1), 5668-5668 (2019-12-13)
Biological nanopores are capable of resolving small analytes down to a monoatomic ion. In this research, tetrachloroaurate(III), a polyatomic ion, is discovered to bind to the methionine residue (M113) of a wild-type α-hemolysin by reversible Au(III)-thioether coordination. However, the cylindrical
Interference of phosphatidylcholines with in vitro cell proliferation?no flock without black sheep
Werlein A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1599-1608 (2015)
Integrative Medicine - E-Book (2017)
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