Product Name
15:0 PC, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, chloroform
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 2.5 mL (850350C-25mg)
pkg of 2 × 4 mL (850350C-200mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850350C
浓度
10 mg/mL (850350C-25mg)
25 mg/mL (850350C-200mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
[P](=O)(OCC[N+](C)(C)C)(OCC(OC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)O
InChI
1S/C38H76NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39(3,4)5)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/p+1
InChI key
LJARBVLDSOWRJT-UHFFFAOYSA-O
一般描述
Phosphatidylcholine (PC) carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
应用
15:0 PC (1,2-dipentadecanoyl-sn-glycero-3-phosphocholine) may be used:
- as a component in fluidizing lipid bilayers to study the role of membrane fluidity in mediating membrane sensitivity to small hydrophobic peptides or haptoglobin-related protein (SHP-1)
- to prepare giant unilamellar lipid vesicles (GUVs)
- to construct supported phospholipid bilayers to study the gel-fluid phase transition behavior using in situ, temperature-dependent atomic force microscopy
生化/生理作用
Phosphatidylcholine (PC) is capable of preventing the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.
包装
5 mL Clear Glass Sealed Ampule (850350C-200mg)
5 mL Clear Glass Sealed Ampule (850350C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
M U Rasheed et al.
The Science of the total environment, 733, 139110-139110 (2020-05-25)
Increased soil nitrogen (N), warming and bark herbivory all are expected to affect boreal forests in the future. We studied the effects of warming (0.5 °C and 4.0 °C above ambient air and soil temperature, respectively), moderate N addition (30 kg N ha-1 y-1) and bark
Thomas Andersen et al.
Soft matter, 10(24), 4268-4274 (2014-05-02)
We reveal that the gel to fluid phase transition causes spherical membrane vesicles to release a finite number of molecules in several consecutive and localized events. By locally melting Giant Unilamellar lipid Vesicles (GUVs), using an optically trapped gold nanoparticle
Z Vivian Feng et al.
Biophysical journal, 88(3), 2154-2164 (2004-12-15)
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the
Yasuhiro Horibata et al.
Scientific reports, 10(1), 2845-2845 (2020-02-20)
StarD7 is a phosphatidylcholine (PC)-specific lipid transfer protein essential for the maintenance of mitochondrial PC composition, morphogenesis, and respiration. Here, we studied the role of StarD7 in skeletal myoblast differentiation using mouse myoblast C2C12 cells and human primary myoblasts. Immunofluorescence
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