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Merck
CN

850366P

Avanti

18:0 (9,10dibromo) PC

Avanti Research - A Croda Brand

别名:

1,2-di-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C44H84NO8PBr4
化学文摘社编号:
分子量:
1105.73
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

18:0 (9,10dibromo) PC, 1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (850366P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850366P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(Br)C(Br)CCCCCCCC)=O)COC(CCCCCCCC(Br)C(Br)CCCCCCCC)=O)=O

General description

18:0 (9,10dibromo) PC (1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine) is a zwitterionic and brominated phospholipid.

Application

18:0 (9,10dibromo) PC (1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine) may be used:
  • in the preparation of liposomes/small unilamellar vesicles (SUVs)
  • in the preparation of large unilamellar vesicles (LUVs) to facilitate vesicles sedimentation
  • as a component in liposomes

Biochem/physiol Actions

Phosphatidylcholine (PC) serves as a surfactant to prevent the penetrance of bacteria. Brominated lipids are capable of recognizing the lipid binding sites on the surface of the reaction center from Rhodobacter sphaeroides.

Packaging

5 mL Clear Glass Sealed Ampule (850366P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids

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Aleksander W Roszak et al.
Biochemistry, 46(11), 2909-2916 (2007-02-24)
This study describes the use of brominated phospholipids to distinguish between lipid and detergent binding sites on the surface of a typical alpha-helical membrane protein. Reaction centers isolated from Rhodobacter sphaeroides were cocrystallized with added brominated phospholipids. X-ray structural analysis
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Maria Jesús Sánchez-Martín et al.
Journal of colloid and interface science, 360(1), 124-131 (2011-05-14)
The aim of this study was to identify proteins that could inhibit the activity of the peptide sequence representing the N-terminal of the surface protein gp41 of HIV, corresponding to the fusion peptide of the virus (HIV-1 FP). To do



全球贸易项目编号

货号GTIN
850366P-10MG04061835230518