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Merck
CN

850368C

Avanti

20:0 PC

Avanti Research™ - A Croda Brand

别名:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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关于此项目

经验公式（希尔记法）:
C48H96NO8P
化学文摘社编号:
61596-53-0
分子量:
846.25
MDL number:
MFCD00067533
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI key

YKIOPDIXYAUOFN-YACUFSJGSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850368C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850368C

concentration

10 mg/mL (850368C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

20:0 PC has been used in collision cross section (CCS) calibration mixture for lipid identification.
It may be used:
  • as a component in giant unilamellar vesicles (GUVs) for a two-photon fluorescence microscopy study
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization
  • as a component in giant unilamellar vesicles (GUVs) to study its interaction with Crotalus atrox-secreted phospholipase A2 (sPLA2)

Biochem/physiol Actions

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation. It can serve as a surfactant to block the penetrance of bacteria by generating a hydrophobic surface.

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
The mucosal layer of the colon has phosphatidylcholine (PC) as a vital constituent.

Packaging

5 mL Clear Glass Sealed Ampule (850368C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

wgk

WGK 3

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

法规信息

危险化学品
易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Susana A Sanchez et al.
Biophysical journal, 82(4), 2232-2243 (2002-03-28)
We describe the interaction of Crotalus atrox-secreted phospholipase A2 (sPLA2) with giant unilamellar vesicles (GUVs) composed of single and binary phospholipid mixtures visualized through two-photon excitation fluorescent microscopy. The GUV lipid compositions that we examined included 1-palmitoyl-2-oleoyl-phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
The Use of LipidIMMS Analyzer for Lipid Identification in Ion Mobility-Mass Spectrometry-Based Untargeted Lipidomics
Ion Mobility-Mass Spectrometry, 269-282 (2020)
L A Bagatolli et al.
Biophysical journal, 79(1), 434-447 (2000-06-27)
Giant unilamellar vesicles (GUVs) composed of different phospholipid binary mixtures were studied at different temperatures, by a method combining the sectioning capability of the two-photon excitation fluorescence microscope and the partition and spectral properties of 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan) and Lissamine rhodamine
Devaki A Kelkar et al.
Biochimica et biophysica acta, 1768(5), 1103-1113 (2007-02-27)
The matching of hydrophobic lengths of integral membrane proteins and the surrounding lipid bilayer is an important factor that influences both structure and function of integral membrane proteins. The ion channel gramicidin is known to be uniquely sensitive to membrane
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