产品名称
20:1 (Cis) PC, Avanti Research™ - A Croda Brand
InChI
1S/C48H92NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,46H,6-19,24-45H2,1-5H3/b22-20-,23-21-/t46-/m1/s1
InChI key
AEUCYCQYAUFAKH-DITNKEBASA-N
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCC/C=C\CCCCCCCC)=O)=O
description
1,2-dieicosenoyl-sn-glycero-3-phosphocholine
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850396P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) may be used:
- as an internal standard for mass spectrometric analysis
- to prepare large multilamellar vesicles for proteoliposome generation
- to study the effects of the lipid chain length on 6-bromoacetyl-2-dimethylaminonaphthalene (BADAN) fluorescence parameters
Biochem/physiol Actions
Phosphatidylcholine (PC) is known to participate in the fusion and transport of membranes.
General description
20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It has two 20 carbon fatty acid chains, each having one cis double bond at the 11th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Packaging
5 mL Clear Glass Sealed Ampule (850396P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Larisa E Cybulski et al.
Current biology : CB, 20(17), 1539-1544 (2010-08-14)
Thermosensors are ubiquitous integral membrane proteins found in all kinds of life. They are involved in many physiological roles, including membrane remodeling, chemotaxis, touch, and pain [1-3], but, the mechanism by which their transmembrane (TM) domains transmit temperature signals is
Rob B M Koehorst et al.
Biophysical journal, 94(10), 3945-3955 (2008-02-01)
The work presented here describes a new and simple method based on site-directed fluorescence labeling using the BADAN label that permits the examination of protein-lipid interactions in great detail. We applied this technique to a membrane-embedded, mainly alpha-helical reference protein
Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Hanninen S, et al.
Bio-protocol, 7(9) (2017)
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.
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