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Merck
CN

850530O

Avanti

7.7 MAG

Avanti Research - A Croda Brand

别名:

1-(7Z-十四烷酰)-rac-丙三醇

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关于此项目

经验公式(希尔记法):
C17H32O4
化学文摘社编号:
分子量:
300.43
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

7.7 MAG, Avanti Research - A Croda Brand 850530O

assay

>99% (TLC)

form

oil

mol wt

300.43 g/mol

packaging

pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))

manufacturer/tradename

Avanti Research - A Croda Brand 850530O

technique(s)

protein sequencing: suitable

shipped in

dry ice

storage temp.

−20°C

Application

7.7 MAG可用作MdfA(多药转运蛋白)-YN1074(Fab片段)复合物中的宿主脂质,用于通过脂质立方相(LCP)法进行结晶。

Biochem/physiol Actions

单酰甘油(MAG)在食品工业中可用作乳化剂。7.7 MAG参与一种外膜蛋白BtuB(维生素B12转运蛋白)的介晶结晶。它还有助于助溶菌酶晶体生长。7.7 MAG在衍射级晶体的生长中也起着关键作用。MAG在制药和食品行业中有重要意义。

General description

单酰甘油(MAG)是甘油酯。7.7 MAG有14个碳酰基链,双层厚度为25.8Å。
这种新的脂质洗涤剂可用于利用脂质中间相结晶膜蛋白。该方法在不同方面被称为脂质立方相或细观法。该方法已被证明是相当通用的,因为它已被用于解析原核和真核蛋白质的 X 射线晶体学结构,即单体、同源和异源多聚体、含生色团和无生色团的蛋白质,以及 α 螺旋和 β 桶蛋白质。

Packaging

5 mL 带螺旋盖的 PTFE 瓶 (850530O-200mg)
5 mL 带螺旋盖的 PTFE 瓶 (850530O-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids


历史批次信息供参考:

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Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Synthesis and characterization of monoacylglycerols through glycerolysis of ethyl esters derived from linseed oil by green processes
Hobuss CB, et al.
Royal Society of Chemistry Advances, 10, 2327-2336 (2020)
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance

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