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关于此项目
经验公式(希尔记法):
C19H36O4
化学文摘社编号:
分子量:
328.49
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
7.9 MAG, Avanti Research™ - A Croda Brand 850534O
InChI
1S/C19H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h9-10,18,20-21H,2-8,11-17H2,1H3/b10-9-
InChI key
OWGMAJRKMYGYBQ-KTKRTIGZSA-N
SMILES string
OCC(O)COC(CCCCC/C=C\CCCCCCCC)=O
assay
>99% (TLC)
form
oil
mol wt
328.49 g/mol
packaging
pkg of 2 × 100 mg (with screw cap (850534O-200mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850534O
technique(s)
protein sequencing: suitable
shipped in
dry ice
storage temp.
−20°C
Application
7.9 MAG适合用作滴定的基质脂质,以避免在进样过程中形成层状结晶相(Lc) 它也适用于介观结晶。
Biochem/physiol Actions
7.9 MAG是一种非单油性脂质。它可以支持细菌视紫红质(一种不可或缺的膜蛋白)的结晶。
General description
这种新型脂质洗涤剂可用于通过使用脂质中间相结晶膜蛋白。该方法在不同方面被称为脂质立方相或细观法。该方法已被证明是相当通用的,因为它已被用于解析原核和真核蛋白质的 X 射线晶体学结构,即单体、同源和异源多聚体、含生色团和无生色团的蛋白质,以及 α 螺旋和 β 桶蛋白质。
Packaging
容量为 5 mL 的带螺旋盖的 PTFE 瓶 (850534O-200mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
In Meso Crystallization of the Integral Membrane Glycerol 3-Phosphate Acyltransferase with Substrates
Li Z, et al.
Crystal Growth & Design, 18(4), 2243-2258 (2018)
Membrane protein crystallization in lipidic mesophases with tailored bilayers
Misquitta LV, et al.
Structure, 12(12), 2113-2124 (2004)
Preparation and delivery of protein microcrystals in lipidic cubic phase for serial femtosecond crystallography
Ishchenko A, et al.
Journal of Visualized Experiments, (115), e54463-e54463 (2016)
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that
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