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Merck
CN

850702P

Avanti

12:0 PE

Avanti Research - A Croda Brand

别名:

1,2-二十二烷酰基-sn-甘油-3-磷酸乙醇胺; DLPE;PE(12:0/12:0)

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关于此项目

经验公式(希尔记法):
C29H58NO8P
化学文摘社编号:
分子量:
579.75
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

12:0 PE, 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine, powder

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O

InChI

1S/C29H58NO8P/c1-3-5-7-9-11-13-15-17-19-21-28(31)35-25-27(26-37-39(33,34)36-24-23-30)38-29(32)22-20-18-16-14-12-10-8-6-4-2/h27H,3-26,30H2,1-2H3,(H,33,34)

InChI key

ZLGYVWRJIZPQMM-UHFFFAOYSA-N

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850702P-1g)
pkg of 1 × 200 mg (850702P-200mg)
pkg of 1 × 25 mg (850702P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850702P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

1,2-二月桂酰-sn-甘油-3-磷酸乙醇胺(12:0 PE):
  • 作为脂质标准品,用于液相色谱−质谱(LC-MS)方法的优化条件可作为脂质标准品
  • 用于定量植物脂质中的磷酸乙醇胺(PE)的磷脂(PL)标准品
  • 可用于制备阴离子脂质体
  • 可用于制备二元巨型单层囊泡(GUVs)

Biochem/physiol Actions

磷脂酰乙醇胺(PE)在真核细胞膜的结构和功能中起着至关重要的作用。

General description

磷脂酰乙醇胺(PE)是真核细胞中广泛分布的甘油磷脂之一。1,2-二月桂酰基-sn-甘油-3-磷酸乙醇胺(12:0 PE/DLPE)具有铵头基(RNH3+),并具有由11个碳原子组成的烷基链。

Packaging

20 mL透明玻璃螺旋盖小瓶(850702P-1g)
5 mL棕色玻璃螺旋盖小瓶(850702P-200mg)
5 mL棕色玻璃螺旋盖小瓶(850702P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Takehiro Jimbo et al.
Biophysical journal, 110(7), 1551-1562 (2016-04-14)
We investigate a temperature-driven recursive division of binary giant unilamellar vesicles (GUVs). During the heating step of the heating-cooling cycle, the spherical mother vesicle deforms to a budded limiting shape using up the excess area produced by the chain melting
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321, 29-88 (2016)
Oligonucleotide delivery with serum into HeLa cells using polycation liposomes
Mady MM
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 7(1), 69-69 (2007)
K V Damodaran et al.
Biophysical journal, 66(4), 1076-1087 (1994-04-01)
A 250 ps molecular dynamics simulation of the dimyristoylphosphatidylcholine (DMPC)-based lipid bilayer, including explicit water molecules, is reported. The solvent environment of the head groups and other structural properties of the bilayer have been analyzed and compared with experimental results
The influence of DOPC on the permeability of lipid membrane: Detergent solubilization and NMR study
Mady MM
Romanian Journal of Biophysics, 17, 259-267 (2007)

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