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Merck
CN

850758C

Avanti

18:0-18:1 PE

Avanti Research™ - A Croda Brand

别名:

1-octadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; SOPE; PE(18:0/18:1(9Z))

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关于此项目

经验公式（希尔记法）:
C41H80NO8P
化学文摘社编号:
6418-95-7
分子量:
746.05
UNSPSC代码:
12352211

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产品名称

18:0-18:1 PE, 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (850758C-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 850758C

浓度

10 mg/mL (850758C-25mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C21H14Cl2N2O2/c1-12-8-9-18-17(10-12)25-21(27-18)13-4-2-5-14(11-13)24-20(26)15-6-3-7-16(22)19(15)23/h2-11H,1H3,(H,24,26)

InChI key

GKFNHDBVWFEZCJ-UHFFFAOYSA-N

一般描述

Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15−25% of the total lipid in the cells of mammals.

应用

1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (18:0-18:1 PE) may be used:
  • as a component in monomolecular films to verify the formation and characterize the properties of domains
  • in the synthesis of mixed acyl chain 7-nitrobenz-2-oxa-1,3-diazol-4-yl-diacyl-sn-glycero-3-phosphoethanolamine (N-NBD-PE) and (N-lissamine rhodamine B sulfonyl)-diacyl-sn-glycero-3-phosphoethanolamine (N-Rh-PE) probes
  • in the preparation of liposomes

生化/生理作用

Phosphatidylethanolamine (PE) participates in the initiation of autophagy.

包装

5 mL Clear Glass Sealed Ampule (850758C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Paweł Wydro et al.
Biochimica et biophysica acta, 1828(6), 1415-1423 (2013-02-13)
In this work the properties of monomolecular films composed of 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (SOPE) and cholesterol, differing in lipid proportion, were investigated in the context of domain formation in the inner leaflet of membrane. To perform comprehensive analysis of the studied model
W Stillwell et al.
Chemistry and physics of lipids, 104(2), 113-132 (2000-02-11)
A major problem in defining biological membrane structure is deducing the nature and even existence of lipid microdomains. Lipid microdomains have been defined operationally as heterogeneities in the behavior of fluorescent membrane probes, particularly the fluorescence resonance energy transfer (FRET)
Jone Garate et al.
Journal of the American Society for Mass Spectrometry, 31(3), 517-526 (2020-03-05)
Imaging mass spectrometry (IMS) is becoming an essential technique in lipidomics. Still, many questions remain open, precluding it from achieving its full potential. Among them, identification of species directly from the tissue is of paramount importance. However, it is not
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
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