产品名称
18:3 PE, 1,2-dilinolenoyl-sn-glycero-3-phosphoethanolamine, chloroform
InChI key
WIHSZOXPODIZSW-KJIWEYRQSA-N
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCC/C=C\C/C=C\C/C=C\CC)=O
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850795C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850795C
concentration
10 mg/mL (850795C-25mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylethanolamine (PE) is a membrane phospholipid. The types of PE depends on the combination of free fatty acids on the α and β position. PE represents the main phospholipid class bacteria and the second most abundant in eukaryotic cells. PE is zwitterionic. PE is synthesized by Kennedy pathway.
Application
18:3 PE has been used in the preparation of liposomes. It may be suitable for use in the characterization of contact angle in monolayer formation.
Biochem/physiol Actions
Phosphatidylethanolamine (PE) plays a key role in autophagy, apoptosis, membrane fusion, cell cycle and cognitive function. PE is essential for maintaining membrane architecture. PE functions to monitor proper progression of cytokinesis during cell division. PE is the precursor for many biologically active signaling molecules like diacylglycerol and phosphatidic acid.
Packaging
5 mL Clear Glass Sealed Ampule (850795C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Ahu Arslan Yildiz et al.
Colloids and surfaces. B, Biointerfaces, 103, 510-516 (2012-12-25)
A facile method for assembly of biomimetic membranes serving as a platform for expression and insertion of membrane proteins is described. The membrane architecture was constructed in three steps: (i) assembly/printing of α-laminin peptide (P19) spacer on gold to separate
Biomimetic membrane platform: fabrication, characterization and applications
Yildiz AA, et al.
Colloids and Interface Science Communications, 103, 510-516 (2013)
Force-from-lipids gating of mechanosensitive channels modulated by PUFAs
Ridone P, et al.
Journal of the Mechanical Behavior of Biomedical Materials, 79, 158-167 (2018)
Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells
Kaku Y, et al.
Cellular Signalling, 27(9), 1713-1719 (2015)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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