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经验公式(希尔记法):
C16H34NO7P
化学文摘社编号:
分子量:
383.42
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
08:0 Lyso PC, 1-octanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder
InChI key
ZVPMBHRQDPDKEF-OAHLLOKOSA-N
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC)=O
assay
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form
powder
packaging
pkg of 1 × 25 mg (855275P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 855275P
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Lysophosphatidylcholine (Lyso-PC) is linked to inflammatory diseases and atherosclerosis. It enhances the expression of genes for growth factors and cellular adhesion molecules.
General description
Lysophosphatidylcholine (Lyso-PC) is a constituent of blood plasma, vascular tissue and lipoproteins. It is a bioactive proinflammatory lipid, produced on pathological response.
Packaging
5 mL Clear Glass Sealed Ampule (855275P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous quantification of mammal lysophosphatidylcholines and lysophosphatidylethanolamines in serum
Suarez-Garcia S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1055, 86-97 (2017)
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)
R E Stafford et al.
Biochemistry, 28(12), 5113-5120 (1989-06-13)
The critical micelle concentration (cmc) of several lysophospholipids and of a lysophospholipid analogue was determined from surface tension measurements using the maximum bubble pressure method and/or 31P NMR. The use of the maximum bubble pressure method has now been extended
商品
The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn
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