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文件

安全信息

855675C

Avanti

1-十六酰-SN-丙三醇-磷酸胆碱

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

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别名:
1-十六烷酰基-sn-甘油-3-磷酸胆碱；PC(16:0/0:0)
经验公式（希尔记法）:
C24H50NO7P
CAS号:
17364-16-8
分子量:
495.63
NACRES:
NA.25

检测方案

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (855675C-25mg)
pkg of 2 × 4 mL (855675C-200mg)

制造商/商品名称

Avanti Polar Lipids 855675C

浓度

10 mg/mL (855675C-25mg)
25 mg/mL (855675C-200mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key

ASWBNKHCZGQVJV-HSZRJFAPSA-N

相关类别

应用

16:0 Lyso PC溶血磷脂酰胆碱已用于揭示脂肪细胞炎性小体在高半胱氨酸诱导的胰岛素抵抗中的核心作用。还用于脂质提取和质谱分析。

包装

5 mL透明玻璃密封安瓿(855675C-200mg)
5 mL透明玻璃密封安瓿(855675C-25mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

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货号
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包装规格/数量

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Xinyuan Li et al.
Redox biology, 28, 101373-101373 (2019-11-16)
It has been shown that anti-inflammatory cytokines interleukin-35 (IL-35) and IL-10 could inhibit acute endothelial cell (EC) activation, however, it remains unknown if and by what pathways IL-35 and IL-10 could block atherogenic lipid lysophosphatidylcholine (LPC)-induced sustained EC activation; and
Song-Yang Zhang et al.
EBioMedicine, 31, 202-216 (2018-05-08)
The adipose Nod-like receptor protein 3 (NLRP3) inflammasome senses danger-associated molecular patterns (DAMPs) and initiates insulin resistance, but the mechanisms of adipose inflammasome activation remains elusive. In this study, Homocysteine (Hcy) is revealed to be a DAMP that activates adipocyte
Oxidized phospholipids inhibit the formation of cholesterol-dependent plasma membrane nanoplatforms
Brameshuber M, et al.
Biophysical Journal, 110(1), 205-213 (2016)
Li V Yang et al.
Blood, 105(3), 1127-1134 (2004-09-24)
G2A is a G-protein-coupled receptor (GPCR) involved in immune regulation. Previous studies have shown that lysophosphatidylcholine (LPC), a bioactive lipid associated with atherosclerosis and autoimmunity, acts through G2A to induce diverse biologic effects. Production of LPC during cell apoptosis serves
Takafumi Enomoto et al.
Langmuir : the ACS journal of surfaces and colloids, 34(3), 750-755 (2017-10-06)
A major goal of synthetic biology is the development of rational methodologies to construct self-assembling non-natural membranes, which could enable the efficient fabrication of artificial cellular systems from purely synthetic components. However, spatiotemporal control of artificial membrane formation remains both
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

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