855777C
Avanti
20:0 Lyso PC
Avanti Research™ - A Croda Brand
别名:
1-eicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/0:0)
描述
1-arachidoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform
方案
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
表单
liquid
包装
pkg of 1 × 2.5 mL (855777C-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
浓度
10 mg/mL (855777C-25mg)
运输
dry ice
储存温度
−20°C
一般描述
Lysophosphatidylcholine (Lyso-PC) is a component of blood plasma, vascular tissue and lipoproteins.
应用
20:0 Lyso PC has been used as an internal standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) to quantify very long chain fatty acids (VLCFA) levels in peroxisome biogenesis disorders (PBD) cell lines.
生化/生理作用
Lysophosphatidylcholine (Lyso-PC) is associated with inflammatory diseases and atherosclerosis. It stimulates the expression of genes for growth factors and cellular adhesion molecules.
包装
5 mL Clear Glass Sealed Ampule (855777C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous quantification of mammal lysophosphatidylcholines and lysophosphatidylethanolamines in serum
Suarez-Garcia S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1055, 86-97 (2017)
The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders
Law KB, et al.
Autophagy, 13(5), 868-884 (2017)
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Kelsey B Law et al.
Autophagy, 13(5), 868-884 (2017-05-20)
Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
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