产品名称
06:0 Lyso PA, 1-hexanoyl-2-hydroxy-sn-glycero-3-phosphate (ammonium salt), chloroform
SMILES string
O[C@](COP([O-])(O)=O)([H])COC(CCCCC)=O.[NH4+]
assay
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (857119C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857119C
concentration
10 mg/mL (857119C-25mg)
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
General description
Lysophosphatidic acid (LPA) is the major component of serum. It has a free hydroxyl and phosphate moiety. LPA is hydrophilic and is not associated with the membrane.
Application
06:0 Lyso PA has been used for the quantification of lipopolysaccharide (LPS) (endotoxin) levels in various commercial and pharmaceutical grade preparations.
Biochem/physiol Actions
Lysophosphatidic acid (LPA) acts as the precursor for the synthesis of phospholipids in eukaryotes and prokaryotes. It prevents differentiation of neuroblastoma and myoblast, supports in neurotransmitter release and smooth muscle contraction. LPA plays a vital role in tissue healing and wound regeneration. It binds to G-protein coupled receptors. LPA has mitogenic properties. It functions as an intercellular signaling molecule. LPA is involved in the initiation of neuropathic pain.
Packaging
5 mL Clear Glass Sealed Ampule (857119C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
新产品
此项目有
Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Inoue M, et al.
Nature Medicine, 10(7), 712-712 (2004)
Lysophosphatidic acid: G-protein signalling and cellular responses
Moolenaar WH, et al.
Current Opinion in Cell Biology, 9(2), 168-173 (1997)
Lysophosphatidic acid, a multifunctional phospholipid messenger
Moolenaar WH
The Journal of Biological Chemistry, 270(22), 12949-12952 (1995)
Lipopolysaccharide is a frequent and significant contaminant in microglia-activating factors
Weinstein JR, et al.
Glia, 56(1), 16-26 (2008)
Jesica R Williams et al.
The Journal of biological chemistry, 284(25), 17304-17319 (2009-04-16)
Lysophosphatidic acid (LPA) is a ligand for LPA(1-3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4-8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship (SAR) of GPR92/LPA(5) is limited and whether LPA is its
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持