857136C
Avanti
18:1 BMP (R,R)
sn-(1-oleoyl-2-hydroxy)-glycerol-3-phospho-sn-3′-(1′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), chloroform
别名:
bis(monoacyl-glycerol)phosphate, lysobisphosphatidic acid; LBPA
方案
>99% (BMP (contains 30% positional isomers), TLC)
表单
chloroform solution
包装
pkg of 1 × 1 mL (857136C-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857136C
浓度
5 mg/mL (857136C-5mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP(OC[C@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
一般描述
18:1 BMP (R,R)/Lysobisphosphatidic acid (LBPA) is an unconventional phospholipid. It is usually present in late endosomes. It is also termed as bis(monoacyl-glycerol)phosphate.
生化/生理作用
18:1 BMP (R,R)/Lysobisphosphatidic acid (LBPA) can modulate endosomal cholesterol levels. It participates in cholesterol transport. LBPA helps to regulate the cholesterol storage capacity of endosomes.
包装
5 mL Clear Glass Sealed Ampule (857136C-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
新产品
此项目有
The stereochemical configuration of lysobisphosphatidic acid from rat liver, rabbit lung and pig lung
Joutti A, et al.
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 450(2), 206-209 (1976)
Lysobisphosphatidic acid controls endosomal cholesterol levels
Chevallier J, et al.
The Journal of Biological Chemistry, 283(41), 27871-27880 (2008)
Elena Zaitseva et al.
PLoS pathogens, 6(10), e1001131-e1001131 (2010-10-16)
Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that infects up to 100 million people each
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