产品名称
VPC 01091, Avanti Research™ - A Croda Brand 857345P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (857345P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857345P
lipid type
phospholipids
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
N[C@](C1)(CO)CC[C@@H]1C2=CC=C(CCCCCCCC)C=C2
General description
VPC 01091是一种鞘氨醇类似物。
该产品受专利号 US 7,754,703 的保护。Avanti 经弗吉尼亚大学许可制造该产品。
Biochem/physiol Actions
VPC 01091是一种选择性鞘氨醇1-磷酸受体-1 (S1PR1) 激动剂和鞘氨醇1-磷酸受体-3 (S1PR3) 拮抗剂。它可在小鼠中提供防缺血再灌注肺损伤保护。
Packaging
5 mL 琥珀色玻璃螺旋盖小瓶（857345P-1mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Matthew L Stone et al.
American journal of physiology. Lung cellular and molecular physiology, 308(12), L1245-L1252 (2015-04-26)
Outcomes for lung transplantation are the worst of any solid organ, and ischemia-reperfusion injury (IRI) limits both short- and long-term outcomes. Presently no therapeutic agents are available to prevent IRI. Sphingosine 1-phosphate (S1P) modulates immune function through binding to a
Byoungjae Kong et al.
Nature communications, 10(1), 185-185 (2019-01-16)
Membrane-disrupting agents that selectively target virus versus host membranes could potentially inhibit a broad-spectrum of enveloped viruses, but currently such antivirals are lacking. Here, we develop a nanodisc incorporated with a decoy virus receptor that inhibits virus infection. Mechanistically, nanodiscs
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 857345P-1MG | 04061835191260 |