857360P
Avanti
VPC 23019
Avanti Research™ - A Croda Brand
别名:
(R)-单磷酸-[2-氨基-2-(3-辛基-苯氨基甲酰)-乙烷基]酯
产品名称
VPC 23019, Avanti Research™ - A Croda Brand 857360P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (857360P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857360P
脂质类型
cardiolipins
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
CCCCCCCCC1=CC(NC([C@H]([NH3+])COP(O)([O-])=O)=O)=CC=C1
InChI
1S/C17H29N2O5P/c1-2-3-4-5-6-7-9-14-10-8-11-15(12-14)19-17(20)16(18)13-24-25(21,22)23/h8,10-12,16H,2-7,9,13,18H2,1H3,(H,19,20)(H2,21,22,23)/t16-/m1/s1
InChI key
MRUSUGVVWGNKFE-MRXNPFEDSA-N
一般描述
VPC 23019是一种芳基酰胺化合物。它是1-磷酸鞘氨醇（S1P）的类似物。
应用
VPC 23019可用于：
- 基于水母发光蛋白的Ca2+检测
- 分析1-磷酸鞘氨醇（S1P）诱导的纤溶酶原激活物抑制剂1（PAI-1）表达的调节作用
- 逆转脂多糖（LPS）处理的小鼠体内载脂蛋白M过表达的保护作用
生化/生理作用
VPC 23019是鞘氨醇-1-磷酸-1（S1P1）和S1P3受体的竞争性拮抗剂。
包装
5 mL棕色玻璃螺旋盖样品瓶（857360P-1mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Eun-Young Kim et al.
Cells, 9(1) (2020-01-16)
The interleukin-22 (IL-22) signaling pathway is well known to be involved in the progression of various cancer types but its role in bone metastatic breast cancer remains unclear. We demonstrate using human GEO profiling that bone metastatic breast cancer displays
Vehicle-dependent effects of sphingosine 1-phosphate on plasminogen activator inhibitor-1 expression
Takahashi C, et al.
Journal of Atherosclerosis and Thrombosis, 37663-37663 (2017)
A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca2+ microdomain in the caveolar compartment
Pulli I, et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 1853(9) (2015)
Sphingosine 1-phosphate analogs as receptor antagonists
Davis MD, et al.
The Journal of biological chemistry, 280(11) (2005)
Apolipoprotein M protects lipopolysaccharide-treated mice from death and organ injury
Kurano M, et al.
Thrombosis and Haemostasis, 118(06) (2018)
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