产品名称
VPC 24191, Avanti Research™ - A Croda Brand 857365P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (857365P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857365P
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCC1=CC=C(NC[C@@H](COP(O)([O-])=O)[NH3+])C=C1
InChI
1S/C17H31N2O4P/c1-2-3-4-5-6-7-8-15-9-11-17(12-10-15)19-13-16(18)14-23-24(20,21)22/h9-12,16,19H,2-8,13-14,18H2,1H3,(H2,20,21,22)/t16-/m0/s1
InChI key
VRQMZRZONPRMOX-INIZCTEOSA-N
Application
VPC 24191 has been used as a sphingosine 1-phosphate (S1P) receptor agonist for various experiments in human bone marrow-derived mesenchymal stem cells overexpressing human telomerase reverse transcriptase (hMSC-TERT) cell treatments and bovine adrenal glomerulosa cells. It has also been used to study its pharmacological properties at the human S1P3 receptor expressed in CHO FlpIn cells.
Biochem/physiol Actions
VPC 24191 acts as a sphingosine 1-phosphate (S1P1/3) receptor agonist.
Packaging
5 mL Amber Glass Screw Cap Vial (857365P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Leyre Brizuela et al.
Journal of lipid research, 48(10), 2264-2274 (2007-07-05)
We reported recently that sphingosine-1-phosphate (S1P) is a novel regulator of aldosterone secretion in zona glomerulosa cells of adrenal glands and that phospholipase D (PLD) is implicated in this process. We now show that S1P causes the phosphorylation of protein
Patrick Quint et al.
The Journal of biological chemistry, 288(8), 5398-5406 (2013-01-10)
Normal bone turnover requires tight coupling of bone resorption and bone formation to preserve bone quantity and structure. With aging and during several pathological conditions, this coupling breaks down, leading to either net bone loss or excess bone formation. To
M Jongsma et al.
British journal of pharmacology, 156(8), 1305-1311 (2009-03-25)
Recently, some ligands targeting the sphingosine-1-phosphate receptor subtype 3 (S1P(3)) have become available. The characterization of these compounds was mainly based on one functional read-out system, although S1P(3) receptors are known to activate different signal transduction pathways. Therefore, this study
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 857365P-1MG | 04061835191321 |