所有图片(4)
About This Item
经验公式(希尔记法):
C25H29BrN4O2
CAS Number:
分子量:
497.43
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
Product Name
VU0359595, (1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (857371P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857371P
脂质类型
bioactive lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
Brc1cc2[nH][c]([n](c2cc1)C3CCN(CC3)C[C@@H](NC(=O)[C@H]4[C@@H](C4)c5ccccc5)C)=O
InChI key
JSVNNLRZCJAYTQ-ORYQWCPZSA-N
一般描述
VU0359595 has been shown to selectively inhibit the PLD1 isoform at nM levels (see data below). **Images added as .gif in folder
应用
VU0359595 has been used as PLD2 (phospholipase D2) inhibitor to quantitatively address functional and molecular aspects of the involvement of PLD-derived phosphatidic acid (PA) in regulated exocytosis and as PLD1 inhibitor to treat the knockout mice to study its effects on them.
生化/生理作用
VU0359595 helps to block phospholipase D (PLD) which in turn reduces deoxyribonucleoside triphosphate (dNTP) biosynthesis in glioma models.
包装
5 mL Amber Glass Screw Cap Vial (857371P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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