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经验公式(希尔记法):
C36H9NO8PD63
化学文摘社编号:
分子量:
741.32
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
14:0 PC-d63, Avanti Research™ - A Croda Brand, powder
SMILES string
[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860347P-10MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) (Lecithins) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH. The fatty acid in PC is mostly palmitic, stearic, oleic, linolenic and arachidonic acid. It is present abundantly in the mammalian membranes. PC is principally synthesized from cytidine diphosphate-choline (CDP-choline). Selective deuteration of this lipid may be used in the structural studies using techniques such as nuclear magnetic resonance (NMR), neutron reflectivity and small-angle neutron scattering.
Biochem/physiol Actions
Phosphatidylcholine (PC) is essential for cholesterol trafficking and membrane cholesterol homeostasis. It acts as the precursor for the synthesis of sphingomyelin. PC plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid.
Packaging
5 mL Amber Glass Screw Cap Vial (860347P-10MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Essentials of Medical Biochemistry (2011)
The Membranes of Cells (2016)
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric S, et al.
Applied Microbiology and Biotechnology, 99(1), 241-254 (2015)
Phosphatidylcholine: greasing the cholesterol transport machinery
Lagace TA
Lipid insights, 8, LPI-S31746 (2015)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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