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经验公式(希尔记法):
C40H9NO8PD71
化学文摘社编号:
分子量:
805.48
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
16:0 PC-d71, Avanti Research™ - A Croda Brand, powder
SMILES string
[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860357P-10MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
technique(s)
mass spectrometry (MS): suitable
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) (Lecithins) is a zwitterion with a quaternary ammonium group and a phosphate moiety in its structure. PC generally possesses saturated fatty acid in the sn-1 position and unsaturated fatty acid at sn-2 position. PC is a strong bilayer forming lipid, present abundantly in mammalian membranes. cytidine diphosphate-choline (CDP-choline) is the precursor for PC synthesis. Selective deuteration of this lipid may have applications in structural studies using techniques such as nuclear magnetic resonance (NMR), neutron reflectivity and small-angle neutron scattering.
Biochem/physiol Actions
Phosphatidylcholine (PC) plays a key role in cholesterol transport and membrane lipid homeostasis. It is the precursor for sphingomyelin synthesis. PC is essential for the synthesis of signaling molecules like diacyl glycerol (DAG), phosphatidic acid and lysophosphatidic acid. 16:0 PC (DPPC) is the key phospholipid in the lipid bilayer of the membranes and also major constituent of lung surfactant.
Packaging
5 mL Amber Glass Screw Cap Vial (860357P-10MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
The Membranes of Cells (2016)
Isotherms of dipalmitoylphosphatidylcholine (DPPC) monolayers: features revealed and features obscured
Klopfer KJ and Vanderlick TK
Journal of Colloid and Interface Science, 182(1), 220-229 (1996)
Essentials of Medical Biochemistry (2011)
Phosphatidylcholine: greasing the cholesterol transport machinery
Lagace TA
Lipid insights, 8, LPI-S31746 (2015)
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric S, et al.
Applied Microbiology and Biotechnology, 99(1), 241-254 (2015)
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