Merck
CN

860384P

Avanti

16:0-d31-18:1 PG

1-palmitoyl-d31-2-oleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] (sodium salt), powder

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别名:
110919
经验公式(希尔记法):
C40H45O10PNaD31
分子量:
802.18
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (860384P-10mg)

制造商/商品名称

Avanti Polar Lipids 860384P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2

InChI

1S/C40H77O10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,37-38,41-42H,3-16,19-36H2,1-2H3,(H,45,46);/q;+1/p-1/b18-17-;/t37?,38-;/m1./s1/i2D3,4D2,6D2,8D2,10D2,12D2,14D2,16D2,19D2,21D2,23D2,25D2,27D2,29D2,31D2;

InChI key

FJXDNGDRHUDFST-YJZUCPFOSA-M

一般描述

氘化脂肪酸经历了α碳上的氘向羰基即C2位的交换,因此将是在该位置上完全氘化和部分氘化的化合物的混合物。

应用

1-棕榈酰基-d31-2-油酰基-sn-甘油-3-[磷酸-rac-(1-甘油)](16:0-d31-18:1 PG)已用作酵母脂质分析的内标。

包装

5 mL透明玻璃密封安瓿(860384P-10mg)

储存分类代码

11 - Combustible Solids


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J P Michel et al.
Langmuir : the ACS journal of surfaces and colloids, 33(41), 11028-11039 (2017-09-19)
The outer membrane (OM) of Gram-negative bacteria is a complex and asymmetric bilayer that antimicrobial peptides must disrupt in order to provoke the cell lysis. The inner and external leaflets of the OM are mainly composed of phospholipids (PL), and
Antonio D Barbosa et al.
Developmental cell, 50(6), 755-766 (2019-08-20)
Cells dynamically adjust organelle organization in response to growth and environmental cues. This requires regulation of synthesis of phospholipids, the building blocks of organelle membranes, or remodeling of their fatty-acyl (FA) composition. FAs are also the main components of triacyglycerols
Nicole Harmouche et al.
Biophysical journal, 115(6), 1033-1044 (2018-09-10)
A synergistic enhancement of activities has been described for the amphipathic cationic antimicrobial peptides magainin 2 and PGLa when tested in antimicrobial assays or in biophysical experiments using model membranes. In the presence of magainin 2, PGLa changes from an
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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