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Merck
CN

860399C

Avanti

16:0-d31-18:1 PC

Avanti Research™ - A Croda Brand

别名:

110918

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关于此项目

经验公式（希尔记法）:
C42H51NO8PD31
化学文摘社编号:
179093-76-6
分子量:
791.27
MDL number:
MFCD00674410
UNSPSC Code:
12352100
NACRES:
NA.25

主要文件

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产品名称

16:0-d31-18:1 PC, 1-palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[H][C@@](COP([O-])(OCC[N+](C)(C)C)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1/i2D3,7D2,9D2,11D2,13D2,15D2,17D2,19D2,22D2,24D2,26D2,28D2,30D2,32D2,34D2

InChI key

WTJKGGKOPKCXLL-KHCKXXADSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (860399C-10mg)
pkg of 1 × 2.5 mL (860399C-25mg)
pkg of 1 × 4 mL (860399C-100mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860399C

concentration

10 mg/mL (860399C-10mg)
10 mg/mL (860399C-25mg)
25 mg/mL (860399C-100mg)

shipped in

dry ice

storage temp.

−20°C

Application

16:0-d31-18:1 PC may be used in the preparation of mitochondrial mimetic liposomes.

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Packaging

5 mL Clear Glass Sealed Ampule (860399C-100mg)
5 mL Clear Glass Sealed Ampule (860399C-10mg)
5 mL Clear Glass Sealed Ampule (860399C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome
Makarova M, et al.
Current Biology (2020)
Rita Touti et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 151, 18-31 (2020-04-11)
Multi-lamellar liposomes (MLLs), prepared by shearing a lamellar phase composed of lipids (phosphatidylcholine) and surfactant (Tween 80®), were designed to control their size, charge and elasticity, the key parameters known to influence liposomes penetration through skin. Their size was tuned
Surface-binding to cardiolipin nanodomains triggers cytochrome c pro-apoptotic peroxidase activity via localized dynamics
Li M, et al.
Structure, 27(5), 806-815 (2019)
Alessandra Luchini et al.
Analytical chemistry, 92(1), 1081-1088 (2019-11-27)
In vitro characterization of membrane proteins requires experimental approaches providing mimics of the microenvironment that proteins encounter in native membranes. In this context, supported lipid bilayers provide a suitable platform to investigate membrane proteins by a broad range of surface-sensitive
Kotaro Hama et al.
Journal of lipid research, 61(4), 523-536 (2020-02-23)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by deleterious mutations in the ABCD1 gene. The ABCD1 protein transports very long-chain FAs (VLCFAs) from the cytosol into the peroxisome where the VLCFAs are degraded through β-oxidation. ABCD1 dysfunction leads to
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