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经验公式（希尔记法）:
C42H81NO2
化学文摘社编号:
分子量:
632.10
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
N-C24:1-deoxysphingosine, N-nervonoyl-1-deoxysphingosine (m18:1/24:1), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860457P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860457P
lipid type
sphingolipids
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
The 1-deoxydihydroceramides are hydrophobic and interact with monolayers and giant unilamellar vesicles. They modulate cell membrane and may affect their biological functionality.
General description
The sphingoid bases sphingosine is acylated with fatty acids with varying acyl-chain resulting in the synthesis of 1-deoxydihydroceramides (1-deoxyDHCers). These deoxyDHCers are further converted to 1-deoxyceramides (1-deoxysphingosine) and 1-(deoxymethyl)ceramides. They are produced by mammals.
Packaging
5 mL Amber Glass Screw Cap Vial (860457P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Biophysical properties of novel 1-deoxy-(dihydro) ceramides occurring in mammalian cells
Jimenez-Rojo N, et al.
Biophysical Journal, 107(12), 2850-2859 (2014)
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now
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