860460P
Avanti
N-C12-deoxysphinganine
Avanti Research™ - A Croda Brand
别名:
N-dodecanoyl-1-deoxysphinganine (m18:0/12:0); N-C12-1-deoxyDHCer; 110958
产品名称
N-C12-deoxysphinganine, N-lauroyl-1-deoxysphinganine (m18:0/12:0), powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (860460P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860460P
运输
dry ice
储存温度
−20°C
一般描述
Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), this product is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-deoxyDHCer is not clearly understood at this time.
N-C12-deoxysphinganine is found in mammalian cells. It may be associated with neuronal toxicity.
包装
5 mL Amber Glass Screw Cap Vial (860460P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
此项目有
Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue
Schwartz NU, et al.
Prostaglandins & other lipid mediators (2019)
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals
Zitomer NC, et al.
The Journal of Biological Chemistry, 284(8), 4786-4795 (2009)
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