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关于此项目
经验公式（希尔记法）:
C29H57NO2
化学文摘社编号:
分子量:
451.77
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
N-C12-desoxymethylsphingosine, Avanti Research™ - A Croda Brand 860466P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860466P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860466P
lipid type
sphingolipids
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCC)=O
InChI key
NQTIAYDGVUCKFJ-KSPVXFDASA-N
General description
Desoxymethylsphingosine is an atypical deoxy-sphingoid base.
Application
N-C12-desoxymethylsphingosine or N-lauroyl-1-desoxymethylsphingosine (m17:1/12:0) has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).
Packaging
5 mL Amber Glass Screw Cap Vial (860466P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Michael S Marshall et al.
PloS one, 13(2), e0193438-e0193438 (2018-02-27)
α-Synuclein aggregation has been linked to Gaucher's disease (GD) and Krabbe's disease (KD), lysosomal conditions affecting glycosphingolipid metabolism. α-Synuclein pathology has been directly attributed to the dysregulation of glycosphingolipids in both conditions, specifically to increased galactosylsphingosine (psychosine) content in the
Michael S Marshall et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 26(3), 874-889 (2018-02-13)
We report a global adeno-associated virus (AAV)9-based gene therapy protocol to deliver therapeutic galactosylceramidase (GALC), a lysosomal enzyme that is deficient in Krabbe's disease. When globally administered via intrathecal, intracranial, and intravenous injections to newborn mice affected with GALC deficiency
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860466P-1MG | 04061835317097 |